Principal (Boston or San Francisco)

Boston, MA
Full Time
Senior Manager/Supervisor

Foreground Capital

About Foreground Capital

Foreground Capital is a San Francisco and Boston-based venture capital firm dedicated to transforming women’s health. Building on our track record of managing one of the largest venture capital portfolios in women’s health, we are now investing out of Fund III, backing early-stage companies across therapeutics, medical devices, diagnostics, and tech-enabled healthcare services.

We invest in breakthrough innovations addressing conditions that affect women uniquely, disproportionately, or differently, targeting significant unmet needs and compelling market opportunities. Our investment strategy is grounded in the belief that transformative innovation, expanded access, affordability, and greater health equity can drive both meaningful improvements in women’s health and strong financial returns

The firm manages more than two dozen portfolio companies, transforming healthcare for nearly one million women nationwide. In 2026, Impact Assets named the team an IA 50 Impact Manager.

The Foreground Capital team spun out of RH Capital in 2024 and continues to manage RH Capital's legacy funds, RH Capital Fund I and II. For more information about Foreground Capital, visit www.foreground.vc.

Principal Position

The Principal will lead and support investments across the full breadth of women's health: therapeutics, medical devices, diagnostics, digital health, and tech-enabled services. This is a senior investing role with significant responsibility and autonomy. The Principal will manage deals end-to-end, from sourcing through diligence, investment recommendation, board representation(including observer or director roles as appropriate), and exit, working closely with the Managing Partners on investment decisions and broader firm priorities.

The Principal will work closely with all team members and report to the Managing Partners of Foreground Capital. The position is based in Boston or San Francisco, with a hybrid work environment and travel as needed.

As part of a small, senior team, this is an opportunity to build a franchise in women's health investing, with a path to Partner for the right candidate.

Responsibilities

The Principal will take significant ownership of investment activities and contribute to the firm's broader priorities across the following areas:

Investing

  • Lead sourcing of high-quality, early-stage investment opportunities across all segments of women's health, building a proprietary pipeline through founders, scientists, clinicians, academic centers, accelerators, and co-investors
  • Develop investment theses in priority areas and identify white space across life sciences, devices, diagnostics, digital health, and tech-enabled services
  • Lead full-cycle due diligence, assessing scientific, clinical, regulatory, reimbursement, commercial, and team risk; engage and manage outside experts and consultants
  • Build and review financial models, valuation, and return analyses appropriate to each business model
  • Author investment memos and present clear, well-supported recommendations to the Managing Partners and Investment Advisory Committee
  • Drive deal execution, including term sheet negotiations, syndicate building, co-investor communications, and coordination with legal counsel

Portfolio

  • Serve as a board director or observer at select portfolio companies, as appropriate
  • Serve as a strategic advisor to founders on clinical development, regulatory and reimbursement strategy, go-to-market, hiring, and follow-on financing
  • Monitor portfolio performance, evaluate follow-on investment opportunities, and develop recommendations on exit strategies
  • Help design and run the firm's portfolio support programs, including founder convenings, webinars, and retreats

Firm Development & External Engagement

  • Support the Managing Partners in fundraising activities, including engagement with current and prospective Limited Partners, LP meetings, preparation of materials, and due diligence
  • Support investor relations, including the annual LP meeting and the Annual Impact Report
  • Represent Foreground at conferences, on panels, and in written thought leadership pieces
  • Build relationships with peer investors, strategics, and industry leaders to strengthen deal flow and syndication

Required Qualifications

  • Demonstrated passion for women's health and its potential to transform care
  • 7+ years of relevant experience, including at least 3–4 years of venture capital investing at a healthcare-focused fund
  • A demonstrated investment track record of sourcing, evaluating, executing and value creation in investments
  • Ability to evaluate opportunities across multiple healthcare business models, with demonstrated depth in at least one (e.g., life sciences, digital health, tech-enabled services, etc.)
  • Ability to assess scientific, clinical, regulatory (FDA), reimbursement, and commercial risk in early-stage companies
  • Deep understanding of the U.S. healthcare ecosystem, including providers, payers, employers, pharma, and medtech
  • Strong financial and analytical skills, including modeling, valuation, and venture return analysis
  • An established network across founders, co-investors, clinicians, and industry
  • Clear, persuasive written and verbal communication, including investment memos and presentations to an investment committee and LPs
  • Sound judgment, high integrity, and the ability to build trust with entrepreneurs, partners, and investors
  • Ability to take ownership of workstreams while collaborating closely with the Managing Partners and broader team in a small, entrepreneurial environment.
  • Bachelor's degree required; an advanced degree (MBA, PhD, or other relevant degree) strongly preferred

Preferred

  • Board or board observer experience at venture-backed companies
  • Operating, clinical, or scientific experience, such as drug or device development, clinical practice, or building a digital health company
  • Experience in multiple segments, for example therapeutics plus digital health or tech-enabled services
  • Prior experience in a women's health or adjacent company or fund
  • Experience supporting fund formation and LP fundraising
  • Demonstrated investment outcomes, including realized exits, markups, or meaningful portfolio value creation

Salary & Benefit Package

  • Competitive base salary, commensurate with experience
  • Participation in carried interest
  • Competitive benefits package
  • Status: Full-time, exempt
Location: This role can be based in San Francisco, CA or Boston, MA.
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